三、教研优势
1.设施和资源FACILITIES AND RESOURCES
The University and Notre Dame Research support more than 20 core facilities and research resources that are available to on-campus researchers as well as external users. These research facilities support a vibrant research community and are fully staffed to provide expert guidance, support, and instrumentation for their users.
这所大学和圣母大学的研究支持了20多个核心设施和研究资源，这些设施和研究资源可以供在校的研究人员和外部用户使用。这些研究机构支持一个充满活力的研究社区，并为他们的用户提供专业的指导、支持和工具。
★环境科学与技术中心
The Center for Environmental Science and Technology (CEST) is a cooperative effort between Notre Dame’s Colleges of Engineering and Science. It fosters interdisciplinary environmental research and education by providing the cutting-edge analytical technologies that are needed in order to address complex environmental issues.CEST has instrumentation in gas chromatography, liquid chromatography, elemental analysis, stable isotope mass spectrometry, and materials characterization, which are all available to Notre Dame faculty, staff, and students without charge. All instruments are maintained by CEST technicians, who are available to train users of all levels on how to use the instruments needed for each research project.
环境科学与技术中心(CEST)是圣母大学工程与科学学院之间的合作努力。它通过提供必要的尖端分析技术来解决复杂的环境问题，促进跨学科的环境研究和教育。环境科学与技术中心在气相色谱、液相色谱、元素分析、稳定同位素质谱和材料表征方面都有仪器都可以在Notre Dame教职员工和学生免费使用。所有仪器由CEST技术人员维护，可以对各个级别的用户进行培训了解如何使用每个研究项目所需的仪器。
★研究计算中心
The Center for Research Computing (CRC) is a leader in cyberinfrastructure development and in data- and compute-intensive research. The CRC manages and provides access to supercomputers, clusters, grid networks, and storage, while lending user support services and expertise to researchers within Notre Dame and external organizations, including industry.The CRC develops computational tools that accelerate scientific inquiry and discovery, including computational modeling, data analysis and management, geographic information systems, and visualization. Additionally, it is an approved Indiana Clinical and Translational Sciences Institute (CTSI) core facility with services available to all CTSI partners.
研究计算中心(CRC)是网络基础设施建设的领导者，数据和计算密集型的研究。研究计算中心管理并提供对超级计算机、集群、网格网络和存储的访问，同时向圣母大学和包括行业在内的外部组织的研究人员提供用户支持服务和专业知识。研究计算中心开发了加速科学探索和发现的计算工具，包括计算建模、数据分析和管理、地理信息系统和可视化。另外，它是一个批准的印第安纳临床和转化科学研究所(CTSI)的核心设施，提供所有CTSI合作伙伴的服务。
★社会研究中心
The Center for Social Research (CSR) improves the quality and efficiency of social research at Notre Dame by working with faculty, students, and staff across all academic disciplines.CSR staff assist with research design, mobile data collection, survey design and administration, data management, statistical consulting, and visualization at any point in a research project’s life cycle, from initial research design through to analyzing and visualizing data.
社会研究中心(CSR)通过与教员，学生，以及所有学术领域的员工合作提高了在圣母大学的社会研究的质量和效率。社会研究中心工作人员协助研究设计、移动数据收集、调查设计和管理、数据管理、统计咨询和可视化，从最初的研究设计到分析和可视化数据。
★化学合成和药物发现(CSDD)设备支持转化生物医学研究
The Chemical Synthesis and Drug Discovery (CSDD) Facility supports translational biomedical research by providing expertise that enables the preparation of small molecules for use in hit verification, lead development, and midsize scale up. It supports the preparation of biological probes (affinity or fluorescently tagged), active pharmaceutical agents as experimental controls, and small chemical libraries for structure-activity relationships and the optimization of pharmacological properties. In addition, the CSDD provides organizational oversight for the Notre Dame Chemical Compound Collection, which has more than 20,000 unique chemical entities.It is available to researchers from the Notre Dame research community, other academic institutions, and industry.
化学合成和药物探索设备(CSDD)支持转化生物医学研究，提供专业知识，使小分子在撞击验证、铅开发和中型规模上的应用。它支持生物探针的制备(亲合或荧光标记)、活性药物作为实验控制，以及结构活性关系的小化学库和药理特性的优化。此外，化学合成和药物探索设备还为圣母大学的化学合成物提供了组织监督，该化合物有超过2万个独特的化学实体。它是来自圣母大学的研究团体、其他学术机构和产业界的研究人员。
★计算机辅助分子设计(CAMD)设备
The Computer Aided Molecular Design (CAMD) Facility provides a full range of computational support, from atomistic modeling to assistance in proposal writing for drug discovery and related areas. With extensive expertise in virtual screening, molecular dynamics simulations, electronic structure calculations, and chemoinformatics modeling, the CAMD can provide valuable services for the interpretation of experimental data and further design of new experiments.Its services are available to Notre Dame researchers, as well as external customers.
计算机辅助分子设计设备(CAMD)提供了一套完整的计算支持，从原子模型到协助药物发现和相关领域的建议写作。在虚拟筛选、分子动力学模拟、电子结构计算和化学信息学建模等方面，计算机辅助分子设计设备可以为实验数据的解释和新实验的进一步设计提供有价值的服务。它的服务可以提供给圣母大学的研究人员和外部客户。
★工程和设计核心设施
With the goal of enhancing the scope and pace of experimental programs across Notre Dame, the Engineering and Design Core Facility (EDCF) offers extensive experience in the development of custom hardware and equipment. From consultation to detailed design work to rapid prototyping and testing, EDCF facilitates the process of going from concept to construction by providing professional engineering support for researchers wishing to develop cutting-edge technologies. Assistance in the areas of electrical, mechanical, software, and systems engineering is currently available. The EDCF welcomes users from all campus departments, as well as other academic and industrial institutions.
为了提高圣母大学的实验项目的范围和速度，工程和设计核心设施(EDCF)在定制硬件和设备的开发方面提供了丰富的经验。从咨询到详细的设计工作到快速的原型设计和测试，EDCF通过为希望开发尖端技术的研究人员提供专业的工程支持，从而促进了从概念到构建的过程。在电气、机械、软件和系统工程方面的帮助目前是可用的。工程和设计核心设施欢迎来自所有校园部门的用户以及其他学术和工业机构的用户。圣母大学的研究团体、外部学术机构和工业开放。
★流式细胞仪设备
The Flow Cytometry Facility is located in the Galvin Life Sciences Center. Equipped with a BD LSRFortessa X-20 system, this cell analyzer delivers high-performance multicolor analysis with a compact footprint. The analyzer is equipped with four lasers (405, 488, 561, 640) to detect up to 16 colors simultaneously to support increasing demands in multicolor flow cytometry. The Flow Cytometry Facility is open to the Notre Dame research community, external academic institutions, and industry.
流式细胞仪设备位于加尔文生命科学中心。配备了BD LSRFortessa X-20系统，该电池分析仪可实现高性能多色分析，占地面积小。分析仪配有四个激光器(405,488,561,640)以同时检测多达16种颜色，以支持多色流式细胞术中日益增长的需求。流式细胞仪设施向圣母大学研究界，外部学术机构和行业开放。
★弗里曼生命科学中心
The Freimann Life Science Center (FLSC) is comprised of two state-of-the-art animal facilities equipped to house a wide variety of vertebrates, including fish, with four zebrafish systems, frogs, rabbits, and rodents. In addition, more than 100 different strains of genetically altered mice are bred and maintained.All animal care staff are certified through the American Association of Laboratory Animal Science or credentialed as Registered Veterinary Technicians who work together with the attending veterinarian to provide humane care for the research animals. The FLSC is fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC).
弗里曼生命科学中心(FLSC)由两个最先进的动物设施组成，设有各种脊椎动物，包括鱼，四个斑马鱼系统，青蛙，兔子和啮齿动物。此外，育种和维持了超过100种不同的遗传改变的小鼠品系。所有动物护理人员都通过美国实验动物科学协会认证，或者被认证为注册兽医技术人员，与兽医合作，为研究动物提供人性化的护理。弗里曼生命科学中心完全由实验动物护理评估和认证协会(AAALAC)认证。
★基因组学和生物信息学核心设施
The Genomics and Bioinformatics Core Facility (GBCF) provides state-of-the-art genomics solutions and data analysis for a broad range of applications, including metagenomics, metagenetics, population genomics, transcriptomics, and epigenomics. The facility offers comprehensive support for a diverse research community that spans basic biomedical research in human disease, pathogen genomics, non-model system genomics, and environmental genomics.The GBCF is a resource available to the Notre Dame research community, external academic institutions, and industry. Additionally, it is an approved Indiana Clinical and Translational Sciences Institute (CTSI) core facility with services available to all CTSI partners.
基因组学和生物信息学核心设施(GBCF)为广泛的应用提供最先进的基因组学解决方案和数据分析，包括宏基因组学，代谢学，群体基因组学，转录组学和表观基因组学。该设施为跨越人类疾病，病原体基因组学，非模型系统基因组学和环境基因组学的基础生物医学研究的多元化研究团体提供全面支持。基因组学和生物信息学核心设施是圣母大学研究界，外部学术机构和行业的资源。此外，它是经过批准的印第安纳临床和转化科学研究所(CTSI)的核心设施，提供给所有基因组学和生物信息学核心设施合作伙伴的服务
★圣母大学综合成像设施
The Notre Dame Integrated Imaging Facility (NDIIF) integrates three areas of Notre Dame imaging expertise: electron microscopy, biological imaging (in vivo imaging and optical microscopy), and histology.The NDIIF has an integrated suite of sophisticated microscopes and imaging stations that enable users to attack the most complex modern research problems. It is open to the Notre Dame research community, external academic institutions, and industry. Additionally, it is an approved Indiana Clinical and Translational Sciences Institute (CTSI) core facility, with services available to all CTSI partners.
圣母大学综合成像设施(NDIIF)整合了圣母大师三项成像专长：电子显微镜，生物成像(体内成像和光学显微镜)和组织学。圣母大学综合成像设施具有一整套复杂的显微镜和成像站，使用户能够攻击最复杂的现代研究问题。对圣母大学研究界，外部学术机构和行业开放。此外，它是经批准的印第安纳临床和转化科学研究所(CTSI)的核心设施，提供给所有CTSI合作伙伴的服务。
★转基因研究中心
The W.M. Keck Center for Transgene Research develops and uses gene-targeting technology to investigate the role of genes in blood coagulation, anticoagulation, and hemostasis in relation to their impact on cancer, infection, and inflammation. Within the Keck Center is the Fluorescence Assisted Cell Sorting Core Facility (FACS), which is shared between the Indiana University School of Medicine in South Bend (IUSM-SB) and Notre Dame. Located in Raclin-Carmichael Hall on the IUSM-SB campus, it houses a BD Biosciences FACSAria III cell sorter, which is available to Notre Dame and IUSM-SB users, as well as other academic institutions on a case-by-case basis.
转基因研究中心开发和使用基因靶向技术来研究基因在凝血，抗凝和止血中的作用，与癌症，感染和炎症的影响有关。Keck中心内是荧光辅助细胞分选核心设施(FACS)，由南本德印第安纳大学医学院(IUSM-SB)和圣母大学共享。位于IUSM-SB校园的Raclin-Carmichael Hall，设有BD Biosciences FACSAria III细胞分选机，可根据具体情况向圣母大学和IUSM-SB用户以及其他学术机构提供。
★圣母院连锁实验生态系统设施
The Notre Dame Linked Experimental Ecosystem Facility (ND-LEEF) is based in South Bend’s St. Patrick’s County Park. It hosts two replicated watersheds that each contain a linked stream, pond, and wetland that can be manipulated to test ecological hypotheses.In addition to the aquatic resources, ND-LEEF has several shallow-groundwater monitoring wells. There are also several acres available for terrestrial research and a large gravel lay-down area for mesocosm experiments. A newly constructed pavilion offers an ideal venue for education and outreach programs.ND-LEEF is available to Notre Dame researchers, other academic institutions, and industry.
圣母院连锁实验生态系统设施(ND-LEEF)位于南本德圣帕特里克县公园。它拥有两个重复的分水岭，每个流域都包含可以被操纵以测试生态假设的链接流，池塘和湿地。除水生资源外，ND-LEEF还有几个浅层地下水监测井。还有几英亩可用于陆地研究和大型砾石沉积区域用于中等体积实验。新建的展馆为教育和外展计划提供了理想场所。ND-LEEF适用于圣母院研究人员，其他学术机构和行业。
★中西部同位素和微量元素研究分析中心
The Midwest Isotope and Trace Element Research Analytical Center (MITERAC) is a National Science Foundation-funded facility that represents a Notre Dame-led consortium of Midwestern universities, including Ball State University, Indiana State University, Indiana University-Purdue University-Indianapolis, Indiana University-South Bend, and Western Michigan University.MITERAC specializes in the elemental and isotopic characterization of environmental, biological, and geological materials, both at the bulk sample and micrometer scales. MITERAC is open to users from the University of Notre Dame.
中西部同位素和微量元素研究分析中心(MITRAC)是国家科学基金会资助的设施，代表圣母大学领导的中西部大学联盟，包括Ball州立大学，印第安纳州立大学，印第安纳大学普渡大学印第安纳州印第安纳波利斯大学大学 - 南本德和西密歇根大学。中西部同位素和微量元素研究分析中心专门从事大量样品和微米尺度的环境，生物和地质材料的元素和同位素表征。中西部同位素和微量元素研究分析中心对圣母大学的用户开放。
★分子结构设施
The Molecular Structure Facility (MSF) provides structural elucidation of new compounds and materials through X-ray diffraction techniques, with two primary services offered: single crystal diffraction and powder diffraction. Single crystal studies can provide the unequivocal three-dimensional connectivity, configuration, and elemental assignment of inorganic, organic, and organometallic compounds, while powder diffraction studies provide bulk sample analysis of new materials.The Molecular Structure Facility is a core facility within the Department of Chemistry and Biochemistry at Notre Dame and provides services for researchers at Notre Dame and the wider academic community.
分子结构设计(MSF)通过X射线衍射技术提供了新的化合物和材料的结构解释，提供了两个主要服务：单晶衍射和粉末衍射。单晶研究可以提供无机，有机和有机金属化合物的明确的三维连通性，配置和元素分配，而粉末衍射研究提供新材料的大量样品分析。分子结构设施是圣母大学化学和生物化学系的核心工作，为圣母大学和更广泛的学术界的研究人员提供服务。
★圣母玛利亚纳米制造设施
The Notre Dame Nanofabrication Facility (NDNF) is a fully equipped Class 100 cleanroom in the Stinson-Remick Hall of Engineering. This facility features a full complement of fabrication, processing, and characterization equipment, as well as the specialized infrastructure required for its proper operation. The facility enables fabrication and characterization of devices with feature sizes from the nanometer to the centimeter scale; typical applications include MEMS actuators and sensors, microfluidic devices, and many others for a wide range of end-use applications and systemsThe facility is available to on campus researchers, as well as external users from industry and the academic community.
圣母玛利亚纳米制造设施(NDNF)是Stinson-Remick工程大楼设备齐全的100级洁净室。该设备具有完整的制造，加工和表征设备，以及正确操作所需的专业基础设施。该设备能够制造和表征具有从纳米到厘米尺度的特征尺寸的器件; 典型的应用包括MEMS致动器和传感器，微流体装置，以及许多其他用于各种终端应用和系统的应用。该设施可用于校园研究人员，以及来自行业和学术界的外部用户。
★物理机械店
The Physics Machine Shop is a full-service design and fabrication shop that serves the entire community with precision in the scientific, medical, mechanical, and artistic disciplines. It uses CNC machine tools and CAD/CAM software to produce complex designs in a wide variety of materials in a timely and cost-effective manner. Working directly from blueprints or drawings provided by the customers, the team can take these ideas and engineer then to the user’s particular needs
物理机械店是一个全方位服务的设计和制造车间，为科学，医学，机械和艺术学科提供精准的整个社区服务。它采用数控机床和CAD / CAM软件，以及时，经济的方式在各种材料中生产复杂的设计。从客户提供的蓝图或图纸直接进行工作，团队可以根据用户的特殊需求，对这些想法和工程进行设计。该店欢迎来自圣母大学的用户。
★辐射实验室的科学玻璃吹制车间
The Radiation Laboratory’s Scientific Glassblowing Shop is the region’s only scientific glassblowing shop and provides services to researchers from across the Notre Dame community, other academic institutions, and industry.The Scientific Glassblowing Shop works with researchers in the design and fabrication of specialty scientific apparatus, as well as to repair or modify existing glassware for specific needs. Fully equipped to handle all custom glassware needs, the Shop also has the capacity to fabricate quartz and borosilicate glassware. Consultation is available on the construction, design, application, and practicalities of glass and other materials used in glass production and scientific research.
辐射实验室的科学玻璃吹制车间是该地区唯一的科学玻璃吹制车间，为来自圣母大学、其他学术机构和工业的研究人员提供服务。科学玻璃吹制车间与研究人员在专业科学仪器的设计和制造中合作，并修复或修改现有的玻璃器皿以满足特定的需要。本公司拥有生产石英玻璃及硼硅酸盐玻璃器皿的能力。在玻璃生产和科研中使用的玻璃和其他材料的建造、设计、应用和实用性方面都有咨询。
★树木遗传核心设施
The Tree Genetics Core Facility provides DNA fingerprinting services for cultivar identification and pedigree analysis for chestnut (Castanea sp.), black walnut (Juglans nigra), Japanese walnut (Juglans ailantifolia), and butternut (Juglans cinerea). Services include genotyping both nuclear and chloroplast genomes.The Tree Genetics Core Facility is available to Notre Dame researchers, as well external users, such as government agencies, private foundations, and individuals.
树木遗传核心设施为板栗，黑胡桃，日本核桃和胡桃胡椒的品种鉴定和谱系分析提供DNA指纹识别服务。服务包括核基因组和叶绿体基因组的基因分型。树遗传核心设施可用于圣母院研究人员以及外部用户，如政府机构，私人基金会和个人。
★辐射实验室的机械车间
The Radiation Laboratory’s Machine Shop provides convenient and flexible services for fabrication, manufacturing, and design of precision research instruments, with specialization in the prototyping, designing, and manufacturing of custom tooling. It produces high quality parts that hold extremely tight tolerances with minimal lead-time. From exotic alloys to common 6061 aluminum, the Shop can machine all types of materials, including machinable glass, plastics, and wood.The Shop can work from prints, sketches, or conceptual ideas to create custom parts and existing parts can be reverse-engineered or altered upon request. It is open to Notre Dame researchers, external academic institutions, or industry.
辐射实验室的机械车间为精密研究仪器的制造，制造和设计提供方便灵活的服务，专门从事定制工具的原型设计，设计和制造。它生产高质量的零件，保证极其严格的公差，交货期最短。从异乎寻常的合金到普通的6061铝，商店可以加工所有类型的材料，包括可机加工的玻璃，塑料和木材。商店可以从印刷，草图或概念思想工作以创建定制零件，现有零件可以根据要求进行反向设计或更改。对圣母院研究人员，外部学术机构或行业开放。
★圣母大学涡轮机械实验室
The Notre Dame Turbomachinery Laboratory (NDTL) is a 25,000 square foot facility located in Downtown South Bend’s Ignition Park. This world-class turbomachinery research and testing facility studies and tests components for the gas turbine engines that are used by commercial and military aircraft, power plants, and the oil and gas industry.The NDTL team provides a full suite of design and procurement services, including 3D modeling and design, analysis, mechanical drawings and fabrication, supply chain management, assembly and installation, component integration, and maintenance. It is available to Notre Dame researchers, other academic institutions, government, and industry.
圣母大学涡轮机械实验室是位于南本德市中心点火公园的2.5万平方英尺的设施。这个世界级的涡轮机械研究和测试设备研究和测试由商用和军用飞机，发电厂和石油和天然气工业使用的燃气轮机的部件。圣母大学涡轮机械实验室团队提供全套设计和采购服务，包括3D建模和设计、分析、机械图纸和制造、供应链管理、组装和安装、组件集成和维护。它可供圣母院研究人员，其他学术机构，政府和行业使用。
